Antitumor Activity of a Pyrrolobenzodiazepine Antibody-Drug Conjugate Targeting LGR5 in Preclinical Models of Neuroblastoma

• Главные авторы: Jianghua Tu (Автор), Yukimatsu Toh (Автор), Adela M. Aldana (Автор), Jake J. Wen (Автор), Ling Wu (Автор), Joan Jacob (Автор), Li Li (Автор), Sheng Pan (Автор), Kendra S. Carmon (Автор), Qingyun J. Liu (Автор)
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• Опубликовано: MDPI AG, 2024-07-01T00:00:00Z.
• Предметы: article
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Neuroblastoma (NB) is a cancer of the peripheral nervous system found in children under 15 years of age. It is the most frequently diagnosed cancer during infancy, accounting for ~12% of all cancer-related deaths in children. Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) is a me...