Elevated doublecortin-like kinase 1 serum levels revert to baseline after therapy in early stage esophageal adenocarcinoma

• Main Authors: Emily M. Christman (Author), Parthasarathy Chandrakesan (Author), Nathaniel Weygant (Author), John T. Maple (Author), William M. Tierney (Author), Kenneth J. Vega (Author), Courtney W. Houchen (Author)
• Format: Book
• Published: BMC, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC) incidence has been increasing in the United States for greater than 30 years. For the majority of EAC patients, treatment is limited and prognosis poor. Doublecortin like kinase-1 (DCLK1) is a cancer stem cell mark...