Structure-Activity Relationship Studies Based on Quinazoline Derivatives as EGFR Kinase Inhibitors (2017-Present)

• Glavni autori: Alexandru Șandor (Autor), Ioana Ionuț (Autor), Gabriel Marc (Autor), Ilioara Oniga (Autor), Dan Eniu (Autor), Ovidiu Oniga (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2023-04-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

The epidermal growth factor receptor (EGFR) plays a critical role in the tumorigenesis of various forms of cancer. Targeting the mutant forms of EGFR has been identified as an attractive therapeutic approach and led to the approval of three generations of inhibitors. The quinazoline core has emerged...