Failure to Thrive in a Middle-Aged Female: A Case of Congenital Incomplete Pancreas From a Rare Genetic Defect

• Main Authors: Onyinye Ugonabo MD (Author), Turki Mohamed MD (Author), Murad Kheetan MD (Author), Ahmed Sherif MD (Author)
• 格式: 图书
• 出版: SAGE Publishing, 2023-04-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Hepatocyte nuclear factor-1 beta (HNF1B) gene is predominantly expressed in the liver, kidney, lung, genitourinary tract, and pancreas. It is an important transcription factor that regulates pancreas development. Mutation or absence of this gene is rare and can cause incomplete pancreatic developmen...