Coexistent sickle-cell anemia and autoimmune disease in eight children: pitfalls and challenges

• Main Authors: Valerie Li- (Author), Florence Uettwiller (Author), Pierre Quartier (Author), Florence Lacaille (Author), Brigitte Bader-Meunier (Author), Valentine Brousse (Author), Mariane de Montalembert (Author)
• Format: Book
• Published: BMC, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Patients with sickle cell disease (SCD) present a defective activation of the alternate complement pathway that increases the risk of infection and is thought to predispose to autoimmune disease (AID). However, coexisting AID and SCD is rarely reported, suggesting possible underd...