Combination of curcumin and piperine synergistically improves pain-like behaviors in mouse models of pain with no potential CNS side effects

• Main Authors: Pawana Boonrueng (Author), Peththa Wadu Dasuni Wasana (Author), Hasriadi (Author), Opa Vajragupta (Author), Pornchai Rojsitthisak (Author), Pasarapa Towiwat (Author)
• Format: Book
• Published: BMC, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Curcumin and piperine are major bioactive compounds of Curcuma longa and Piper nigrum, widely consumed as spices and flock medicine. The combinational use of these plants is a common practice in Southeast Asia. Synergism between curcumin and piperine has been found in several ani...