Dengue viruses infect human megakaryocytes, with probable clinical consequences.

• Main Authors: Megan B Vogt (Author), Anismrita Lahon (Author), Ravi P Arya (Author), Jennifer L Spencer Clinton (Author), Rebecca Rico-Hesse (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

One of the most important clinical signs of dengue virus infection is the reduction of white blood cells and platelets in human peripheral blood (leukopenia and thrombocytopenia, respectively), which may significantly impair the clearance of dengue virus by the immune system. The cause of thrombocyt...