Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia

• Main Authors: Michaela Schäfer (Author), Christian U. Oeing (Author), Maria Rohm (Author), Ezgi Baysal-Temel (Author), Lorenz H. Lehmann (Author), Ralf Bauer (Author), H. Christian Volz (Author), Michael Boutros (Author), Daniela Sohn (Author), Carsten Sticht (Author), Norbert Gretz (Author), Katrin Eichelbaum (Author), Tessa Werner (Author), Marc N. Hirt (Author), Thomas Eschenhagen (Author), Karin Müller-Decker (Author), Oliver Strobel (Author), Thilo Hackert (Author), Jeroen Krijgsveld (Author), Hugo A. Katus (Author), Mauricio Berriel Diaz (Author), Johannes Backs (Author), Stephan Herzig (Author)
• Format: Book
• Published: Elsevier, 2016-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Cancer cachexia affects the majority of tumor patients and significantly contributes to high mortality rates in these subjects. Despite its clinical importance, the identity of tumor-borne signals and their impact on specific peripheral organ systems, particularly the heart, remain mostl...