Granulysin-Bearing Cells in the Skin Lesions of Acute Graft-versus-Host Disease: Possible Mechanisms for Hypohidrosis in Graft-versus-Host Disease

• Main Authors: Sadanori Furudate (Author), Taku Fujimura (Author), Yumi Kambayashi (Author), Setsuya Aiba (Author)
• Formato: Livro
• Publicado em: Karger Publishers, 2013-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Graft-versus-host disease (GVHD) is an important complication of bone marrow transplantation and is known to induce sweat gland abnormalities. We employed immunohistochemical staining for granulysin, dermcidin as well as IL-17 and Foxp3 in the lesional skin of 7 patients with acute GVHD. Granulysin-...