Granulysin-Bearing Cells in the Skin Lesions of Acute Graft-versus-Host Disease: Possible Mechanisms for Hypohidrosis in Graft-versus-Host Disease

Graft-versus-host disease (GVHD) is an important complication of bone marrow transplantation and is known to induce sweat gland abnormalities. We employed immunohistochemical staining for granulysin, dermcidin as well as IL-17 and Foxp3 in the lesional skin of 7 patients with acute GVHD. Granulysin-...

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Main Authors: Sadanori Furudate (Author), Taku Fujimura (Author), Yumi Kambayashi (Author), Setsuya Aiba (Author)
Formato: Livro
Publicado em: Karger Publishers, 2013-04-01T00:00:00Z.
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