Induction of Mitosis Delay and Apoptosis by CDDO-TFEA in Glioblastoma Multiforme

• Main Authors: Tai-Hsin Tsai (Author), Ann-Shung Lieu (Author), Tzuu-Yuan Huang (Author), Aij-Lie Kwan (Author), Chih-Lung Lin (Author), Yi-Chiang Hsu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Glioblastoma multiforme (GBM) is the vicious malignant brain tumor in adults. Despite advances multi-disciplinary treatment, GBM constinues to have a poor overall survival. CDDO-trifluoroethyl-amide (CDDO-TEFA), a trifluoroethylamidederivative of CDDO, is an Nrf2/ARE pathway activator. C...