Compensative Resistance to Erastin-Induced Ferroptosis in GPX4 Knock-Out Mutants in HCT116 Cell Lines

• Autores principales: Malgorzata Adamiec-Organisciok (Autor), Magdalena Wegrzyn (Autor), Lukasz Cienciala (Autor), Damian Sojka (Autor), Joanna Nackiewicz (Autor), Magdalena Skonieczna (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2023-12-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Ferroptosis results from the accumulation of oxidized and damaged lipids which then leads to programmed cell death. This programmed process is iron-dependent, and as a fundamental biological process, plays a crucial role in tissue homeostasis. The ferroptosis molecular pathway depends on self-regula...