Mechanisms of isoniazid and rifampicin-induced liver injury and the effects of natural medicinal ingredients: A review

• Main Authors: Xiuping Zhuang (Author), Li Li (Author), Tianyi Liu (Author), Rui Zhang (Author), Peimin Yang (Author), Xin Wang (Author), Long Dai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Isoniazid (INH) and rifampicin (RFP) are the first-line medications for tuberculosis treatment, and liver injury is the major adverse effect. Natural medicinal ingredients provide distinct benefits in alleviating patients' symptoms, lowering the liver injury risk, delaying disease progression,...