Metabolomic Profiling for Histologically Fibrotic Stage in Chronic Drug-Induced Liver Injury

• Main Authors: Xian He (Author), Ming-Xi Zhou (Author), Cheng Cheng (Author), Shan-Shan Li (Author), Yuan Gao (Author), Zhi-Tao Ma (Author), Xin-Hua Song (Author), Zhao-Fang Bai (Author), Zheng-Sheng Zou (Author), Xiao-He Xiao (Author), Jia-Bo Wang (Author), Ya-Wen Lu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and aims: Chronic drug-induced liver injury (DILI) is a rare but under-researched adverse drug reaction-related disease, which is highly likely to progress into liver fibrosis and even cirrhosis. In this study, metabolomics was used to screen out characteristic metabolites related to the...