A novel small molecule RK-019 inhibits FGFR2-amplification gastric cancer cell proliferation and induces apoptosis in vitro and in vivo

• Main Authors: Jun Zeng (Author), Kai Ran (Author), Xinyue Li (Author), Longyue Tao (Author), Qiwei Wang (Author), Jiangtao Ren (Author), Rong Hu (Author), Yongxia Zhu (Author), Zhihao Liu (Author), Luoting Yu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gastric cancer (GC) is one of the most malignant cancers and is estimated to be fifth in incidence ratio and the third leading cause of cancer death worldwide. Despite advances in GC treatment, poor prognosis and low survival rate necessitate the development of novel treatment options. Fibroblast gr...