Pluripotent anti-inflammatory immunomodulatory effects of papaverine against cerebral ischemic-reperfusion injury

• Main Authors: Shuang Guan (Author), Qiong Liu (Author), Hao Gu (Author), Ying-ying Zhang (Author), Peng-lu Wei (Author), Yi-fei Qi (Author), Jun Liu (Author), Zhong Wang (Author)
• Format: Book
• Published: Elsevier, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The mechanism of the papaverine (PV) for the treatment of cerebral ischemia remains unclear. A total of 42 mice induced with focal cerebral ischemia were randomly divided into three groups: PV,baicalin (BA)and vehicle group. Both PV and BA could significantly reduce the ischemic infarct volume (P &l...