miR-548e Sponged by ZFAS1 Regulates Metastasis and Cisplatin Resistance of OC by Targeting CXCR4 and let-7a/BCL-XL/S Signaling Axis

• Main Authors: Jing Zhang (Author), Li-Ni Quan (Author), Qiu Meng (Author), Hai-Yan Wang (Author), Jie Wang (Author), Pin Yu (Author), Jian-Tao Fu (Author), Ying-Jia Li (Author), Jin Chen (Author), Hong Cheng (Author), Qing-Ping Wu (Author), Xin-Rong Yu (Author), Hong-Ye Yun (Author), Shou-Guo Huang (Author)
• Format: Book
• Published: Elsevier, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ovarian cancer (OC) is a severe malignancy featuring a poor prognosis due to rapid metastasis and chemotherapy resistance. In this study, we extensively investigated the upstream and downstream mechanisms of miR-548e in regulating OC progression and cisplatin resistance. Our results indicated that Z...