Dihydropyridine Calcium Channel Blockers Suppress the Transcription of PD-L1 by Inhibiting the Activation of STAT1

• Hlavní autoři: Xiaohui Pan (Autor), Run Li (Autor), Hongjie Guo (Autor), Wenxin Zhang (Autor), Xiaqing Xu (Autor), Xi Chen (Autor), Ling Ding (Autor)
• Médium: Kniha
• Vydáno: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Programmed death ligand 1 (PD-L1) which is upregulated in various epithelial tumors, plays a central role in the evasion of the immune system. In addition to monoclonal antibodies that blocking PD1/PD-L1 axis, finding small molecule compounds that can suppress PD-L1 expression might be another subst...