Age-Related Increase of Collagen/Fibrin Deposition and High PAI-1 Production in Human Nasal Polyps

• Main Authors: Ara Jo (Author), Tae Gyu Choi (Author), Jung Yeon Han (Author), Mark H. Tabor (Author), Narasaiah Kolliputi (Author), Richard F. Lockey (Author), Seong H. Cho (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Our previous studies showed an age-related increased prevalence of nasal polyps (NP) and reduced production of S100A8/9 in elderly patients with chronic rhinosinusitis with NP (CRSwNP). In this study, we investigated an unbiased age-related gene expression profile in CRSwNP subjects and h...