Comparative study of cold hyperalgesia and mechanical allodynia in two animal models of neuropathic pain: different etiologies and distinct pathophysiological mechanisms.

• Main Authors: Carlos Henrique Alves Jesus (Author), Franciele Franco Scarante (Author), Anne Karoline Schreiber (Author), Aléxia Thamara Gasparin (Author), Daiany Darlly Bello Redivo (Author), Evelize Stacoviaki Rosa (Author), Joice Maria da Cunha (Author)
• Format: Book
• Published: Universidade de São Paulo, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Neuropathic pain (NP) affects more than 8% of the global population. The proposed action of the transient receptor potential ankyrin 1 (TRPA1) as a mechanosensor and the characterization of the transient receptor potential melastatin 8 (TRPM8) as a cold thermosensor raises the question of w...