Рerisinusoidal-centrolobular liver fibrosis: features of morphogenegis and parameters of progression
Abstract The research of morphogenesis of liver fibrosis in 589 patients with chronic viral hepatitis, alcoholic and non-alcoholic steatohepatitis has shown that perisinusoidal-centrоlobular liver fibrosis can develop at chronic liver diseases. This type of liver fibrosis is characterized by collage...
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| Main Authors: | , |
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| Format: | Book |
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Zaporozhye State Medical University,
2012-12-01T00:00:00Z.
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| Summary: | Abstract The research of morphogenesis of liver fibrosis in 589 patients with chronic viral hepatitis, alcoholic and non-alcoholic steatohepatitis has shown that perisinusoidal-centrоlobular liver fibrosis can develop at chronic liver diseases. This type of liver fibrosis is characterized by collagen deposition and fibrosis in perisinusoidal space of Disse in 3rd-2nd zones of liver acinus and around centrolobular veins at minimal or absent portal fibrosis. Severe perisinusoidal-central-lobular liver fibrosis is manifested by symptoms of portal hypertention before cirrhosis development. |
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| Item Description: | 10.14739/2310-1237.2012.3.17012 2306-8027 2310-1237 |