Notch 1 signaling pathway is the potential target of novel anticancer drugs for the treatment of human nasopharyngeal cancer

• Main Authors: Guo-Fang Guan (Author), De-Jun Zhang (Author), Ding Xin (Author), Lian-Ji Wen (Author), Duo-Jiao Yu (Author), Yan-Qing Lu (Author), Yan Zhao (Author), Tie-Jun Wang (Author)
• Format: Book
• Published: Bangladesh Pharmacological Society, 2014-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Activation of Notch signaling pathway in cancer stem cells plays a crucial role in the regulation of selfrenewal and maintenance of side population cells.  In the present study, we have identified cancer stem like 2.7% side population cells from nasopharyngeal carcinoma samples whose prevalence was...