OLIG2 is a novel immunohistochemical marker associated with the presence of PAX3/7-FOXO1 translocation in rhabdomyosarcomas

• Main Authors: Magdalena Kaleta (Author), Anna Wakulińska (Author), Agnieszka Karkucińska-Więckowska (Author), Bożenna Dembowska-Bagińska (Author), Wiesława Grajkowska (Author), Maciej Pronicki (Author), Maria Łastowska (Author)
• Format: Book
• Published: BMC, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The most frequent histological types of rhabdomyosarcoma (RMS) in children are embryonal (ERMS) and alveolar (ARMS) tumours. The majority of ARMS are characterized by the presence of PAX3/7-FOXO1 gene fusion and have a worse prognosis than fusion gene-negative ARMS. However, iden...