Iodine-induced synthetic method and pharmacokinetic study of cis- and trans-crocetin

• Main Authors: Boshen Li (Author), Yuxuan Zhang (Author), Zhiqiang Yang (Author), Xiaolin Li (Author), Jun Yang (Author), Kai Luo (Author), Renjie Wang (Author), Chengrong Xiao (Author), Maoxing Li (Author), Yue Gao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective:This experiment aimed to obtain the relatively rare cis-crocetin isomer from natural plants, which predominantly exist in the more stable all-trans configuration. This was achieved through iodine-induced isomerization, followed by purification and structural identification. The study also...