Strongyloides stercoralis and HTLV-1 coinfection in CD34+ cord blood stem cell humanized mice: Alteration of cytokine responses and enhancement of larval growth.

• Main Authors: Lauren E Springer (Author), John B Patton (Author), Tingting Zhan (Author), Arnold B Rabson (Author), Hsin-Ching Lin (Author), Tim Manser (Author), James B Lok (Author), Jessica A Hess (Author), David Abraham (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Viral and parasitic coinfections are known to lead to both enhanced disease progression and altered disease states. HTLV-1 and Strongyloides stercoralis are co-endemic throughout much of their worldwide ranges resulting in a significant incidence of coinfection. Independently, HTLV-1 induces a Th1 r...