Use of blinatumomab and CAR T-cell therapy in children with relapsed/refractory leukemia: A case series study

• Autori principali: Songmi Wang (Autore), Aiguo Liu (Autore), Na Wang (Autore), Yaqin Wang (Autore), Ai Zhang (Autore), Li Wang (Autore), Wen Yu (Autore), Chunrui Li (Autore), Yicheng Zhang (Autore), Qun Hu (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

BackgroundThe 5-year event-free survival rate for childhood acute lymphoblastic leukemia (ALL) has increased to more than 85%. However, the 5-year overall survival rate in children with relapsed/refractory ALL did not exceed 50%. In the past decade, immunotherapies (such as blinatumomab and chimeric...