Use of blinatumomab and CAR T-cell therapy in children with relapsed/refractory leukemia: A case series study

• Main Authors: Songmi Wang (Author), Aiguo Liu (Author), Na Wang (Author), Yaqin Wang (Author), Ai Zhang (Author), Li Wang (Author), Wen Yu (Author), Chunrui Li (Author), Yicheng Zhang (Author), Qun Hu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundThe 5-year event-free survival rate for childhood acute lymphoblastic leukemia (ALL) has increased to more than 85%. However, the 5-year overall survival rate in children with relapsed/refractory ALL did not exceed 50%. In the past decade, immunotherapies (such as blinatumomab and chimeric...