Oligonucleotide Therapeutics: From Discovery and Development to Patentability

• Auteurs principaux: Lara Moumné (Auteur), Anne-Céline Marie (Auteur), Nicolas Crouvezier (Auteur)
• Format: Livre
• Publié: MDPI AG, 2022-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Following the first proof of concept of using small nucleic acids to modulate gene expression, a long period of maturation led, at the end of the last century, to the first marketing authorization of an oligonucleotide-based therapy. Since then, 12 more compounds have hit the market and many more ar...