Transformation of t(14;18)-negative follicular lymphoma to plasmablastic lymphoma: a case report with analysis of genetic evolution

• Main Authors: Sojung Lim (Author), Jiwon Koh (Author), Jeong Mo Bae (Author), Hongseok Yun (Author), Cheol Lee (Author), Jin Ho Paik (Author), Tae Min Kim (Author), Yoon Kyung Jeon (Author)
• Format: Book
• Published: BMC, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Follicular lymphoma (FL) is characterized by t(14;18)(q32;q21) involving the IGH and BCL2 genes. However, 10-15% of FLs lack the BCL2 rearrangement. These BCL2-rearrangement−negative FLs are clinically, pathologically, and genetically heterogeneous. The biological behavior and hi...