Effects of Tamoxifen on L-Glutamate Transporters of Astrocytes
Tamoxifen (Tam) decreased the clearance of L-glutamate (L-Glu) by cultured astrocytes at 1 pM, 1 nM, and 1 μM, but became toxic at 10 μM. When L-Glu transporters were mostly inhibited by threo-β-benzyloxyaspartate (TBOA) (1 mM) or D,L-threo-β-hydroxyaspartate (THA) (1 mM), Tam (1 nM) did not change...
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| Main Authors: | , , , , |
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| Format: | Book |
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Elsevier,
2008-01-01T00:00:00Z.
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