Cytoprotective Effect of 3-[2-[4-(3-Chloro-2-methylphenyl)-1-piperazinyl] ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole Dihydrochloride 3.5 Hydrate (DY-9760e) Against Ischemia/Reperfusion-Induced Injury in Rat Heart Involves Inhibition of Fodrin Breakdown and Protein Tyrosine Nitration

• Главные авторы: Masami Hashimoto (Автор), Yoko Takada (Автор), Yusuke Takeuchi (Автор), Jiro Kasahara (Автор), Hiroaki Hisa (Автор), Yasufumi Shirasaki (Автор), Kohji Fukunaga (Автор)
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• Опубликовано: Elsevier, 2005-01-01T00:00:00Z.
• Предметы: article
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We here assessed the effects of 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl] ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate (DY-9760e), a novel calmodulin antagonist, on infarct size in the rat heart subjected to ischemia/reperfusion. Rats were subjected to a...