Systemic HIV-1 infection produces a unique glial footprint in humanized mouse brains

Studies of innate glial cell responses for progressive human immunodeficiency virus type one (HIV-1) infection are limited by a dearth of human disease-relevant small-animal models. To overcome this obstacle, newborn NOD/SCID/IL2Rγc−/− (NSG) mice were reconstituted with a humanized brain and immune...

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Autores principales: Weizhe Li (Autor), Santhi Gorantla (Autor), Howard E. Gendelman (Autor), Larisa Y. Poluektova (Autor)
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Publicado: The Company of Biologists, 2017-12-01T00:00:00Z.
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