Plackett-Burman design in robustness testing of liquid chromatographic method for determination of sodium-valproat

• Main Authors: Kojić-Marinković Slavica (Author), Tumbas Mihaela (Author), Rakić Tijana (Author), Jančić-Stojanović Biljana (Author)
• Format: Book
• Published: Pharmaceutical Association of Serbia, Belgrade, Serbia, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this paper, application of Plackett-Burman design in robustness testing of liquid chromatographic method for determination of sodium valproate. As factors which could have influence on method's robustness content of acetonitrile, concentration of sodium dihydrogenphosphate, pH of the mobile...