Piperacillin Steady State Concentrations in Target Tissues Relevant for PJI Treatment-A Randomized Porcine Microdialysis Study Comparing Continuous Infusion with Intermittent Short-Term Infusion

• Main Authors: Hans Christian Rasmussen (Author), Pelle Hanberg (Author), Martin Knudsen (Author), Sara Kousgaard Tøstesen (Author), Andrea René Jørgensen (Author), Elisabeth Krogsgaard Petersen (Author), Kristina Öbrink-Hansen (Author), Kjeld Søballe (Author), Maiken Stilling (Author), Mats Bue (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

(1) Introduction: Piperacillin is a common antibiotic choice in the treatment of periprosthetic joint infections (PJI) caused by <i>Pseudomonas aeruginosa</i>. The aim of this study was to assess and compare the time with free piperacillin concentration above the minimum inhibitory conce...