Effects of a long-acting secretin peptide analog alone and in combination with a GLP-1R agonist in a diet-induced obesity mouse model

• Главные авторы: Mona Loeffler (Автор), Katarina Klepac (Автор), Angela Baljuls (Автор), Bradford Hamilton (Автор), Svenja Mayer-Wrangowski (Автор), Peter Haebel (Автор), Tina Zimmermann (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2023-08-01T00:00:00Z.
• Предметы: article
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Objective: Obesity is a major global health problem which can be targeted with new mechanistic diverse pharmacological interventions. Here we evaluate a new long-acting secretin receptor agonist as a potential treatment for obesity. Methods: BI-3434 was designed as a secretin analog with stabilized...