IN VITRO IRREVERSIBLE BINDING AND DEGRADATION OF (R)- AND (S)-KETOPROFEN GLUCURONIDES TO PLASMA PROTEINS

This study describes the in vitro degradation studies of the diastereomeric ketoprofen glucuronides, under physiological conditions (pH 7.4, 37°C, (R)-ketoprofen glucuronide t½ = 30 min, (S)-ketoprofen glucuronide t½ = 70 min) and the irreversible binding of diastereomeric ketoprofen glucuronides (1...

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Bibliographic Details
Main Authors: PETER J. HAYBALL (Author), KELLIE L. TUCK (Author)
Format: Book
Published: Universiti Sains Malaysia, 2007-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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