PINK1 mediated mitophagy attenuates early apoptosis of gingival epithelial cells induced by high glucose

• Main Authors: Chunhui Zhu (Author), Ying Zhao (Author), Dandan Pei (Author), Zhongbo Liu (Author), Jin Liu (Author), Ye Li (Author), Shuchen Yu (Author), Lingyan Ma (Author), Junyi Sun (Author), Ang Li (Author)
• Format: Book
• Published: BMC, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Oxidative stress mediated by hyperglycemia damages cell-reparative processes such as mitophagy. Down-regulation of mitophagy is considered to be a susceptible factor for diabetes mellitus (DM) and its complications. However, the role of mitophagy in DM-associated periodontitis ha...