Inducers of Senescence, Toxic Compounds, and Senolytics: The Multiple Faces of Nrf2-Activating Phytochemicals in Cancer Adjuvant Therapy

• Main Authors: Marco Malavolta (Author), Massimo Bracci (Author), Lory Santarelli (Author), Md Abu Sayeed (Author), Elisa Pierpaoli (Author), Robertina Giacconi (Author), Laura Costarelli (Author), Francesco Piacenza (Author), Andrea Basso (Author), Maurizio Cardelli (Author), Mauro Provinciali (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The reactivation of senescence in cancer and the subsequent clearance of senescent cells are suggested as therapeutic intervention in the eradication of cancer. Several natural compounds that activate Nrf2 (nuclear factor erythroid-derived 2-related factor 2) pathway, which is involved in complex cy...