Multidrug Resistance Reversal Effects of Aminated Thioxanthones and Interaction with Cytochrome P450 3A4

Purpose. Aminated thioxanthones have recently been described as dual-acting agents: growth inhibitors of leukemia cell lines and P-glycoprotein (P-gp) inhibitors. To evaluate the selectivity profile of thioxanthones as inhibitors of multidrug resistance (MDR), their interaction with other ABC transp...

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Main Authors: Andreia Palmeira (Author), Maria Emília Sousa (Author), Miguel X Fernandes (Author), Madalena M. Pinto (Author), M. Helena Vasconcelos (Author)
Format: Book
Published: Frontiers Media S.A., 2011-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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