Updated carrier rates for c.35delG (GJB2) associated with hearing loss in Russia and common c.35delG haplotypes in Siberia

• Main Authors: Marina V. Zytsar (Author), Nikolay A. Barashkov (Author), Marita S. Bady-Khoo (Author), Olga A. Shubina-Olejnik (Author), Nina G. Danilenko (Author), Alexander A. Bondar (Author), Igor V. Morozov (Author), Aisen V. Solovyev (Author), Valeriia Yu. Danilchenko (Author), Vladimir N. Maximov (Author), Olga L. Posukh (Author)
• Format: Book
• Published: BMC, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Mutations in GJB2 gene are a major causes of deafness and their spectrum and prevalence are specific for various populations. The well-known mutation c.35delG is more frequent in populations of Caucasian origin. Data on the c.35delG prevalence in Russia are mainly restricted to t...