Targeted Co-Delivery of Docetaxel and cMET siRNA for Treatment of Mucin1 Overexpressing Breast Cancer Cells

• Main Authors: Naime Majidi Zolbanin (Author), Reza Jafari (Author), Jafar Majidi (Author), Fatemeh Atyabi (Author), Mehdi Yousefi (Author), Farhad Jadidi-Niaragh (Author), Leili Aghebati-Maleki (Author), Dariush Shanehbandi (Author), Mohammad-Sadegh Soltani Zangbar (Author), Alireza Mohajjel Nayebi (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Targeted treatment of breast cancer through combination of chemotherapeutic agents and siRNA had been drawing much attention in recent researches. This study was carried out to evaluate mucin1 aptamer-conjugated chitosan nanoparticles containing docetaxel and cMET siRNA on SKBR3 cells. Meth...