Inhibition of lncRNA XIST Improves Myocardial I/R Injury by Targeting miR-133a through Inhibition of Autophagy and Regulation of SOCS2

• Hoofdauteurs: Zhiqiang Li (Auteur), Yaping Zhang (Auteur), Nan Ding (Auteur), Yudong Zhao (Auteur), Zankai Ye (Auteur), Lei Shen (Auteur), Hanlu Yi (Auteur), Yaobin Zhu (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2019-12-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The objective of this study was to investigate the role of lncRNA XIST and its relationship with miR-133a in myocardial I/R injury. H9C2 cells treated by hypoxia/reoxygenation (H/R) were used to establish an in vitro I/R model. The small interfering RNA (siRNA) for XIST and miR-133 mimics, inhibitor...