A Carbon 21 Steroidal Glycoside with Pregnane Skeleton from <em>Cynanchum atratum</em> Bunge Promotes Megakaryocytic and Erythroid Differentiation in Erythroleukemia HEL Cells through Regulating Platelet-Derived Growth Factor Receptor Beta and JAK2/STAT3 Pathway

• Main Authors: Jue Yang (Author), Chaolan Pan (Author), Yang Pan (Author), Anlin Hu (Author), Peng Zhao (Author), Meijun Chen (Author), Hui Song (Author), Yanmei Li (Author), Xiaojiang Hao (Author)
• Format: Book
• Published: MDPI AG, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Erythroleukemia is a rare form of acute myeloid leukemia (AML). Its molecular pathogenesis remains vague, and this disease has no specific therapeutic treatments. Previously, our group isolated a series of Carbon 21 (C-21) steroidal glycosides with pregnane skeleton from the root of <i>Cynanch...