GO-Y078, a Curcumin Analog, Induces Both Apoptotic Pathways in Human Osteosarcoma Cells via Activation of JNK and p38 Signaling

• Main Authors: Peace Wun-Ang Lu (Author), Renn-Chia Lin (Author), Jia-Sin Yang (Author), Eric Wun-Hao Lu (Author), Yi-Hsien Hsieh (Author), Meng-Ying Tsai (Author), Ko-Hsiu Lu (Author), Shun-Fa Yang (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteosarcoma is the most common primary bone malignancy in teenagers and continues to confer a generally poor prognosis due to its highly metastatic potential. Poor solubility in water and instability of curcumin limits its bioavailability for use in the adjuvant situation to improve the prognosis a...