Distinct Functions of the Primate Putamen Direct and Indirect Pathways in Adaptive Outcome-Based Action Selection

• Main Authors: Yasumasa Ueda (Author), Ko Yamanaka (Author), Atsushi Noritake (Author), Kazuki Enomoto (Author), Naoyuki Matsumoto (Author), Hiroshi Yamada (Author), Kazuyuki Samejima (Author), Hitoshi Inokawa (Author), Yukiko Hori (Author), Kae Nakamura (Author), Minoru Kimura (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cortico-basal ganglia circuits are critical regulators of reward-based decision making. Reinforcement learning models posit that action reward value is encoded by the firing activity of striatal medium spiny neurons (MSNs) and updated upon changing reinforcement contingencies by dopamine (DA) signal...