Dual-responsive nanoparticles with transformable shape and reversible charge for amplified chemo-photodynamic therapy of breast cancer

• Main Authors: Wenfeng Jia (Author), Rui Liu (Author), Yushan Wang (Author), Chuan Hu (Author), Wenqi Yu (Author), Yang Zhou (Author), Ling Wang (Author), Mengjiao Zhang (Author), Huile Gao (Author), Xiang Gao (Author)
• Format: Book
• Published: Elsevier, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Herein, we designed a dual-response shape transformation and charge reversal strategy with chemo-photodynamic therapy to improve the blood circulation time, tumor penetration and retention, which finally enhanced the anti-tumor effect. In the system, hydrophobic photosensitizer chlorin e6 (Ce6), hyd...