Dual-responsive nanoparticles with transformable shape and reversible charge for amplified chemo-photodynamic therapy of breast cancer

• Autors principals: Wenfeng Jia (Autor), Rui Liu (Autor), Yushan Wang (Autor), Chuan Hu (Autor), Wenqi Yu (Autor), Yang Zhou (Autor), Ling Wang (Autor), Mengjiao Zhang (Autor), Huile Gao (Autor), Xiang Gao (Autor)
• Format: Llibre
• Publicat: Elsevier, 2022-08-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Herein, we designed a dual-response shape transformation and charge reversal strategy with chemo-photodynamic therapy to improve the blood circulation time, tumor penetration and retention, which finally enhanced the anti-tumor effect. In the system, hydrophobic photosensitizer chlorin e6 (Ce6), hyd...