Validation of an RP-HPLC Method for the Determination of Asenapine Maleate in Dissolution Media and Application to Study In Vitro Release from Co-Crystals

Asenapine maleate is an antipsychotic drug that is indicated in the treatment of schizophrenia and bipolar disorders. It has low aqueous solubility and high permeability (Class II drug) and undergoes an extensive first pass effect. These problems result in low oral bioavailability (<2%). To enhan...

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Bibliographic Details
Main Authors: Suhair S. Al-Nimry (Author), Mai S. Khanfar (Author)
Format: Book
Published: MDPI AG, 2021-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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