Decoding the anti-Leishmania braziliensis activity of 1,10-phenanthroline-5,6-dione and its silver- and copper-based complexes: In vitro and in vivo approaches

• Main Authors: André L.S. Santos (Author), Ana Karina C. Lima (Author), Simone S.C. Oliveira (Author), Rosiane F. dos Santos (Author), Michael Devereux (Author), Malachy McCann (Author), Marta H. Branquinha (Author), Patrícia M.L. Dutra (Author)
• Format: Book
• Published: Elsevier, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leishmaniasis is a neglected tropical disease, whose chemotherapy still presents a series of severe side effects for the patient. Recently, our group published the leishmanicidal action of 1,10-phenanthroline (1), 1,10-phenanthroline-5,6-dione (phendione, 2) and its silver(I) [Ag(phendione)2]ClO4 (3...