Mutational Characteristics of Causative Genes in Chinese Hereditary Spherocytosis Patients: a Report on Fourteen Cases and a Review of the Literature

• Main Authors: Dong Wang (Author), Li Song (Author), Li Shen (Author), Kaihui Zhang (Author), Yuqiang Lv (Author), Min Gao (Author), Jian Ma (Author), Ya Wan (Author), Zhongtao Gai (Author), Yi Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Hereditary spherocytosis (HS), characterized by the presence of spherocytic red cells in peripheral blood, hemolysis, splenomegaly, jaundice, and gallstones, is a common form of inherited hemolytic anemia (HA). To date, five causative genes associated with HS have been identified, includ...