Lin28 affects the proliferation and osteogenic differentiation of human dental pulp stem cells by directly inhibiting let-7b maturation

• Main Authors: Liu Yan (Author), Jing Sun (Author), Yushan Wang (Author), Xinxin Liu (Author), Jiayi Hu (Author), Mengxin Sun (Author), Xi Suo (Author), Rongquan Duan (Author), Changyong Yuan (Author)
• Format: Book
• Published: Nature Publishing Group, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objective Activation of Lin28 gene under certain conditions promotes tissue damage repair. However, it remains unknown whether conditional expression of Lin28 facilitates the recovery of damaged pulp tissue. In the study, we focus on exploring the effects and possible regulatory mechanisms...