cGMP compliant one-step, one-pot automated [18F]FBnTP production for clinical imaging of mitochondrial activity

Abstract Background 4-[18F]fluorobenzyl-triphenylphosphonium ([18F]FBnTP) is a lipophilic cation PET tracer. The cellular uptake of [18F]FBnTP is correlated with oxidative phosphorylation by mitochondria, which has been associated with multiple critical diseases. To date, [18F]FBnTP has been success...

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Hoofdauteurs: Mai Lin (Auteur), Cong-Dat Pham (Auteur), Robert T. Ta (Auteur), H. Charles Manning (Auteur)
Formaat: Boek
Gepubliceerd in: SpringerOpen, 2024-06-01T00:00:00Z.
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